Wood等(1971)曾报导蚕蚀性角膜溃疡(Mooren氏溃疡)可分两种类型:(1)单眼、局限性、能手术治愈的;(2)顽固进展性双侧型,可导致整个角膜基质的破坏,并对药物和手术治疗均无效,尔后角膜变薄,新生血管形成,以致角膜完全混浊,结膜上皮复盖。至此晚期,角膜溃疡才消退。作者应用7.5 mm穿通性角膜移植治疗蚕蚀性角膜溃疡病变静止后至少4个月的晚期角膜混浊患者,获得预期效果。 (1971) reported that Mooren’s ulcer (Mooren’s ulcer) can be divided into two types: (1) monocular, localized, surgically curable; (2) refractory progressive bilateral type can lead to the entire cornea Matrix destruction, and drug and surgical treatment are ineffective, and later corneal thinning, angiogenesis, resulting in complete corneal opacity, conjunctival epithelial coverage. At this later stage, corneal ulcers subsided. The authors applied 7.5 mm penetrating keratoplasty to treat patients with advanced corneal opacity who have been at rest for at least 4 months after Mooren ’s disease was at rest, and obtained the expected results.