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作者报道38例原发性肾小球疾病肾活检病理诊断与临床诊断。38例中慢性肾小球肾炎16例,其光镜病理论断为系膜增殖性肾小球肾炎(MsPGN)7例,微小病变(MCD)3例,膜增殖性肾小球肾炎(MPGN)2例,局灶性肾小球硬化(FGS)3例,新日体性肾小球肾炎(CGN)1例。隐匿性肾小球疾病8例,其中MsPGN 5例,MCD,FGS及不能诊断各1例。肾病综合征7例,其中MCD3例,MsPGN、MPGN、FGS和终未期固缩肾(ESCK)各1例。其他临床诊断共7例,其中毛细血管内增殖性肾炎(PEGN)2例,MCD,CGN,CGN,ESCK,MPGN和MsPGN各1例。上述结果表明,病理诊断同临床诊断无固定性联系,但有倾向性联系。MsPGN共14例,有浮肿7例和蛋白尿10例中的8例经治疗后浮肿和蛋白尿消失,而血尿有7例仅3例消失。MCD共8例,有浮肿7例,蛋白尿5例,经治疗后均消失。由此说明MCD和MsPGN的浮肿及蛋白尿治效好,而MsPGN血尿疗效差。MPGN和FGS共9例,上述3项指标疗效均差。
The authors report 38 cases of primary glomerular disease renal biopsy pathological diagnosis and clinical diagnosis. Thirty-six cases of chronic glomerulonephritis were observed in 38 cases, including 7 cases of mesangial proliferative glomerulonephritis (MsPGN), 3 cases of minimal change (MCD), 3 cases of proliferative glomerulonephritis (MPGN) 2 Three cases were focal focal glomerulosclerosis (FGS) and one was neonatal glomerulonephritis (CGN). Occult glomerular disease in 8 cases, including 5 cases of MsPGN, MCD, FGS and can not be diagnosed in 1 case. Nephrotic syndrome in 7 cases, including MCD 3 cases, MsPGN, MPGN, FGS and end-stage unilateral nephropathy (ESCK) in 1 case. There were 7 cases of other clinical diagnosis, including 2 cases of capillary proliferative nephritis (PEGN), 1 case of MCD, CGN, CGN, ESCK, MPGN and MsPGN. The above results show that there is no fixed relationship between pathological diagnosis and clinical diagnosis, but there is a tendency to contact. MsPGN a total of 14 cases, 7 cases of edema and 10 cases of proteinuria in 8 cases after treatment, edema and proteinuria disappeared, and 7 cases of hematuria only 3 cases disappeared. MCD a total of 8 cases, 7 cases of edema, proteinuria in 5 cases, after treatment were disappeared. This shows that MCD and MsPGN edema and proteinuria effective, and MsPGN hematuria poor efficacy. MPGN and FGS in 9 cases, the three indicators of poor efficacy.