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对急性肾功能衰竭(ARF)少尿或无尿患者尚缺乏理想疗法,本文在综合治疗ARF同时,应用大剂量速尿治疗10例,其中挤压综合征5例,急性鱼胆中毒2例,急性出血性坏死性小肠炎、急性重度溶血、急性特重型药物过敏性紫癜各1例。除1例死于大咯血性窒息外,均收到良好效果。本文在ARF少尿期应用速尿利尿,当剂量加大至1000mg时能获得意外效果,当日排尿550～870ml。其机理认为速尿能增加皮质血流,有改善肾功能的作用。本组短期应用大剂量速尿,未见有溶血、血尿及听力明显减退现象,
Acute renal failure (ARF) oliguric or anuria patients lack of ideal therapy, this article in the comprehensive treatment of ARF, the application of high-dose furosemide treatment of 10 cases, including 5 cases of crush syndrome, acute fish gall poisoning in 2 cases, Acute hemorrhagic necrotizing enterocolitis, acute severe hemolysis, acute severe drug allergic purpura in 1 case. All patients received good results except one died of hemoptysis. This article in the oliguric ARF application furosemide diuretic, when the dose increased to 1000mg can get unexpected results, the day of voiding 550 ~ 870ml. The mechanism that furosemide can increase cortical blood flow, improve renal function. This group of short-term high-dose furosemide, no hemolysis, hematuria and hearing loss significantly reduced,