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目的：通过对６７例胎儿畸形合并弓形体感染的分析，了解和探索弓形体感染与胎儿畸形的关系及发病学特征。方法：应用双盲和多盲方法进行母血和胎儿体液的血清免疫学检测，畸胎儿尸检和显微镜下查找弓形体以及用畸胎儿脏器组织匀浆后经动物接种盲传。结果：孕妇血清弓形体检出阳性率３３．３％，畸胎儿体液弓形体阳性率５１．６％。畸胎儿的许多脏器内均找到弓形体，动物接种弓形体复合组织接种阳性率高于单纯接种阳性率（Ｐ＜０．０１）。结论：孕妇弓形体感染是生物学致畸的重要因素，早期妊娠弓形体感染如不及时治疗，对胎儿的正常发育影响更大。
Objective: To understand and explore the relationship between Toxoplasma gondii infection and fetal malformations and the characteristics of pathogenesis by analyzing 67 cases of fetal malformation combined with Toxoplasmosis. Methods: Serum immunological tests of maternal serum and fetal fluid were performed by double-blind and multi-blind methods. The autopsies of teratomas and microscopic examination of toxoplasmosis were performed. Results: The positive rate of Toxoplasma gondii in pregnant women was 33.3%, and the positive rate of Toxoplasma gondii Toxoplasma was 51.6%. Toxoplasma was found in many organs of teratocarcinoma. The positive rate of Toxoplasma gondii inoculation was higher than that of inoculation alone (P <0.01). Conclusion: Toxoplasma infection in pregnant women is an important factor in the biological teratogenicity. Toxoplasma infection in early pregnancy, if not treated in time, has a greater impact on the normal development of the fetus.