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丙硫异烟胺(PTH)为杀菌剂,作用仅次于利福平(RMP),但有两个主要缺点:(1)象RMP那样每月用一次会降低疗效;(2)对肝脏的毒性,有的报告说可高达不能接受的程度,甚至引起死亡。作者选择瘤型和界线类病人,细菌指数在3以上,未治或只单用过DDS,开始时均短期住院,后转门诊继续治疗,监督服药和做DDS尿测定。各种检查均于疗前及以后每隔3个月进行一次。30％的病人还于疗前及6个月后进行过鼠足垫接种。评定肝的状况时分为:①黄疸,②亚临床黄
PTH is a fungicide, second only to rifampicin (RMP), but has two major drawbacks: (1) once a month as RMP reduces the efficacy; (2) Toxicity, some reports say up to unacceptable levels, and even cause death. The authors selected tumor type and borderline patients, the bacterial index of more than 3, untreated or only used DDS, were the beginning of short-term hospitalization, the transfer to the clinic for continued treatment, supervision of medication and DDS urine determination. Various examinations are conducted every 3 months before and after treatment. Thirty percent of patients also received footpad inoculation before and 6 months after treatment. Assessment of the condition of the liver is divided into: ① jaundice, ② subclinical yellow