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学者认为,多靶点的药物治疗可能是内毒素性休克防治的重要研究方向[1-2]。中药具有多靶点作用,对内毒素性多器官功能障碍的防治具有重要价值。利胆排毒口服液是我们结合国内外研究成果,动物实验表明,其用于内毒素血症疗效显著。该口服液配方已获国家发明专利(专利号:ZL 2007100511818.6)。为保证该制剂的质量,我们对其进行了质量标准制订研究。1仪器与试药1.1仪器Waters 600高效液相色谱仪、Waters 2996二极管阵列检测
Scholars believe that multi-target drug treatment may be an important research direction of endotoxic shock [1-2]. Chinese medicine has a multi-target role in the prevention and treatment of endotoxin-induced multiple organ dysfunction has an important value. Li gall detoxification oral solution is our combination of research results at home and abroad, animal experiments show that its efficacy for the treatment of endotoxemia significantly. The oral liquid formula has won the national invention patent (Patent No .: ZL 2007100511818.6). To ensure the quality of the preparation, we conducted a quality standard formulation study. 1 instruments and reagents 1.1 instrument Waters 600 high performance liquid chromatography, Waters 2996 diode array detection