目的:为了解NSAID引起的胃肠道副作用 。方法:分析1986—1992年因其所致上消化道出血226例。结果:住院比例逐年增高,56.2％发病前无症状,35.4％和14.2％,9例穿孔;69.9％为急性胃十二指肠粘膜麋烂、应激性溃疡出血,30.1％为慢性溃疡出血。结论:①诱发急性慢性溃疡:②不论年龄、使用时间长短均可发生胃十二指肠粘膜损害致严重并发症。 Purpose: To understand the gastrointestinal side effects caused by NSAIDs. Methods: 226 cases of upper gastrointestinal bleeding from 1986 to 1992 were analyzed. Results: The proportion of hospitalizations increased year by year, 56.2% were asymptomatic before onset, 35.4% and 14.2%, 9 were perforation, 69.9% were mucosal mucosa of acute gastroduodenal mucosa, hemorrhagic stress ulcer and 30.1% hemorrhage of chronic ulcer. Conclusions: ①Acute chronic ulcer induced: ② Regardless of age, duration of use may cause severe complications of gastroduodenal mucosal damage.