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目的观察米索前列醇用于高龄孕妇妊娠期高血压疾病患者剖宫产预防产后出血的效果。方法选择2011年6月-2012年6月天津市职业病防治院妇产科120例择期剖宫产的高龄初产妊娠期高血压疾病产妇,无用药禁忌症,随机分为观察组和对照组,观察组60例,胎儿娩出后宫体肌内注缩宫素20U,肛内置入米索前列醇400μg;对照组60例,胎儿娩出后子宫体肌内注射20U缩宫素,同时静脉滴注20U缩宫素。观察两组产后2h及24h出血量。结果两组产后2h及24h出血量差异有统计学意义(P<0.01)。结论高龄孕妇妊娠期高血压疾病患者择期剖宫产术应用米索前列醇400μg置肛内促进子宫收缩强于缩宫素,能有效预防产后出血,且用药方便,副反应少。
Objective To observe the effect of misoprostol on cesarean section prevention of postpartum hemorrhage in elderly pregnant women with gestational hypertension. Methods Select June 2011 - June 2012 Tianjin Occupational Disease Prevention and Treatment Hospital, Obstetrics and Gynecology 120 cases of elective cesarean section of primiparous women with gestational hypertension hypertension contraindications were randomly divided into observation group and control group, The observation group of 60 cases, intrauterine injection of oxytocin 20U intrauterine injection of the fetus, 400ml of misoprostol in the anus; control group of 60 cases, intrauterine injection of 20U oxytocin intramuscular injection of the fetus, while intravenous infusion of 20U shrink Palace element. Two groups of postpartum 2h and 24h bleeding were observed. Results The postoperative 2h and 24h postpartum hemorrhage volume difference was statistically significant (P <0.01). Conclusions Elective cesarean section in elderly pregnant women with gestational hypertension can improve the contractility of the uterus by using misoprostol 400μg, which can effectively prevent postpartum hemorrhage. It is convenient for medication and has few side effects.