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1型糖尿病患者需要规定剂量的胰岛素来控制他们的血糖水平。虽然许多研究都集中在发明更适当的胰岛素释放方法上,但目前仍是利用一个泵或通过每天注射投药。Jerrdd olefsky、Richard Lerner等人最近在《美国科学院学报》上陈述了他们对一种胰岛素释放技术进行初步研究的结果,此项技术有可能大大增加剂量之间的间隔。化学上附加的伪装基团被用于灭活胰岛素,但利用一种催化的抗体可以完全贮备活性,这种抗体可以选择性地去除伪装基团。从理论上讲,给予带有修饰胰岛素的抗体可以使活性胰岛素逐渐地释放。
Patients with type 1 diabetes require a prescribed dose of insulin to control their blood glucose levels. Although many studies have focused on inventing more appropriate insulin delivery methods, it is still currently administered using a pump or by daily injection. Jerrdd Olefsky, Richard Lerner and others recently presented in the Proceedings of the Proceedings of the National Academy of Sciences on their preliminary findings on an insulin release technique that could potentially significantly increase the interval between doses. Chemically attached camouflage groups are used to inactivate insulin, but the activity is fully stocked with a catalytic antibody that selectively removes the masked group. Theoretically, administration of an antibody with modified insulin can gradually release active insulin.