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目的:对比分析阿托伐他汀、辛伐他汀对原发性高脂血症(Primary hyperlipidemia,PH)的临床疗效情况。方法:根据用药方案不同将我院86例PH患者分为对照组43例(应用辛伐他汀)与实验组43例(应用阿托伐他汀);对比两组有效性及安全性。结果:实验组、对照组临床总有效率分别为97.67%、86.05%,P<0.05,差异有统计学意义。实验组、对照组不良反应发生率分别为2.33%、4.65%,P>0.05,差异无统计学意义。结论:与辛伐他汀相比,阿托伐他汀的临床疗效更佳,值得临床广泛应用及实践。
Objective: To compare and analyze the clinical effect of atorvastatin and simvastatin on primary hyperlipidemia (PH). Methods: 86 PH patients in our hospital were divided into control group (43 cases) and experimental group (43 cases) (atorvastatin group) according to different medication regimen. The effectiveness and safety of the two groups were compared. Results: The total clinical effective rate in experimental group and control group was 97.67% and 86.05%, respectively, P <0.05, the difference was statistically significant. The incidence of adverse reactions in experimental group and control group were 2.33% and 4.65%, respectively, P> 0.05, but the difference was not statistically significant. Conclusion: Compared with simvastatin, atorvastatin has better clinical efficacy and is worthy of clinical application and practice.