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嘌呤类药物作用及巯基嘌呤甲基转移酶遗传多态性的研究进展梁爱斌综述顾龙君审校目前研究结果表明，治疗急性淋巴细胞白血病（ＡＬＬ）的抗嘌呤代谢药物——６－巯基嘌呤（６－ＭＰ）和６－巯代鸟嘌呤（６－ＴＧ）均是无内在生物活性的药物，必须通过体内一系列代谢后才能...
Purine drugs and the research progress of genetic polymorphisms of thiopurine methyltransferase Liang Aibin review Gu Longjun review the current results show that the treatment of acute lymphoblastic leukemia (ALL) anti-purine metabolism drugs - 6-mercaptopurine (6- MP) and 6-thioguanine (6-TG) are drugs without intrinsic biological activity, must pass through a series of metabolic in vivo ...