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Four new diorganotin complexes were synthesized and characterized by IR and 1H NMR.Their in vitro antitumor activities against a series of human tumor cell lines such as P 388 tumor cells were tested.The results showed that the complexes mainly exhibited strong antitumor activities against P 388 ,but presented no activities against other tumor cell lines.The structure activity relationships were discussed.
Four new diorganotin complexes were synthesized and characterized by IR and 1H NMR. The in vitro antitumor activities against a series of human tumor cell lines such as P 388 tumor cells were tested. The results showed the combination primarily cheerful strong antitumor activities against P 388 , but presented no activities against other tumor cell lines. The structure activity relationships were discussed.