论文部分内容阅读
目的观察中西医结合治疗缓解期心绞痛的临床疗效及分析血清炎性因子水平。方法选取医院收治的缓解期心绞痛患者108例作为研究对象,随机分为对照组和观察组,每组54例。对照组采用西医硝酸酯制剂等治疗,观察组在对照组基础上给予中药益心舒胶囊治疗。观察2组临床治疗效果及血清高敏C反应蛋白(hs CRP)、肿瘤坏死因子(TNF)-α、白细胞介素(IL)-6的水平。结果观察组治疗总有效率为90.7%,高于对照组的74.1%(P<0.05)。治疗后,2组血清hs CRP、TNF-α和IL-6水平均下降,且观察组血清hs CRP、TNF-α和IL-6水平低于对照组(P均<0.05)。结论中药益心舒胶囊结合常规药物治疗缓解期心绞痛临床疗效显著,血清炎性因子水平明显降低,可进一步在临床推广应用。
Objective To observe the clinical curative effect of angina pectoris treated with integrated traditional Chinese and western medicine and to analyze the serum levels of inflammatory cytokines. Methods A total of 108 patients with angina pectoris undergoing remission were selected as the study subjects and randomly divided into control group and observation group with 54 cases in each group. The control group was treated with western medicine nitrate preparation. The observation group was treated with Yixinshu capsule on the basis of the control group. The clinical curative effect and serum hs-CRP, TNF-α, IL-6 levels were observed in two groups. Results The total effective rate in the observation group was 90.7%, which was higher than that in the control group (74.1%, P <0.05). After treatment, the serum levels of hsCRP, TNF-α and IL-6 in both groups decreased, and the levels of hsCRP, TNF-α and IL-6 in the observation group were lower than those in the control group (all P <0.05). Conclusions The clinical curative effect of traditional Chinese medicine Yixinshum capsule combined with routine drug treatment of angina pectoris is significant, the level of serum inflammatory factor is significantly reduced, which can be further popularized and applied in clinic.