1肝癌肝移植术后复发转移的机制肿瘤的发生是一个多步骤、多环节的过程,其分子机制涉及癌基因、抑癌基因、转移相关基因、生长因子及其受体、黏附分子及细胞外基质的合成降解、肿瘤血管生成以及机体免疫等多个环节[1],其转移的过程包括:原发灶癌细胞恶性增殖→新生血管形成→癌 The mechanism of recurrence and metastasis of liver cancer after liver transplantation The occurrence of tumor is a multi-step and multi-step process, the molecular mechanism involves oncogenes, tumor suppressor genes, metastasis-related genes, growth factors and their receptors, adhesion molecules and extracellular Matrix synthesis and degradation, tumor angiogenesis and immune and other aspects [1], the transfer process includes: primary malignant tumor cells proliferation → neovascularization → cancer