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据报道狂犬病病毒(RV)是通过与肌肉神经元突触膜上的乙酰胆碱受体(AchR)结合而侵犯神经。RV结合AchR的位点在其外膜糖蛋白的第190～203位氨基酸区段。用人工合成该氨基酸序列的多肽免疫小鼠而获得抗此多肽的单克隆抗体(McAb2PV36～74),
Rabies virus (RV) is reported to invade nerves by binding to the acetylcholine receptor (AchR) on the synaptic membrane of muscle neurons. The site of RV binding to AchR is at amino acid residues 190-203 of its outer membrane glycoprotein. Mice were immunized with a synthetic peptide of this amino acid sequence to obtain a monoclonal antibody against this polypeptide (McAb 2 PV 36-74)