论文部分内容阅读
《氯喹、非那根、强的松治小儿支气管哮喘》一文发表后(见本刊1982年第一期),有许多读者和患儿家长来信反映,此法有一定的实用价值,有较好的治疗效果.但同时也提出了一些问题.以下谈谈我们的认识和体会,供参考.一.氯喹治支气管哮喘的作用机理及其副作用:使用氯喹治疗哮喘主要在于氯喹能通过稳定溶酶体膜,阻止蛋白酶对激肽类释放的诱导影响,阻止白细胞趋化反应,减弱其吞噬作用;并有轻度的抗组织胺作用,从而能减轻腺体分泌、粘膜水肿和缓解支气管平滑肌痉挛。我们对婴幼儿非顽固性的病例,一般采用胆碱能阻滞剂654—2治疗哮喘.可
After the publication of “Chloroquine, Pinagone and Prednisone Pediatric Bronchial Asthma” (see the first issue of 1982), there are many readers and parents of children complain that this method has some practical value and has good The treatment effect, but also raised some questions.Let’s talk about our understanding and experience for reference.Methods: The mechanism and side effects of chloroquine bronchial asthma: The use of chloroquine for the treatment of asthma mainly consists of chloroquine by stabilizing the lysosomal membrane , To prevent the induction of the release of kinin protease, to prevent leukocyte chemotactic response, weakening its phagocytosis; and mild antihistamine effect, which can reduce glandular secretion, mucosal edema and bronchial smooth muscle spasm. We are non-refractory cases of infants and young children, the general use of cholinergic blockers 654-2 for the treatment of asthma.