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目的探讨超敏C反应蛋白(hs-CRP)水平与脑梗死患者病情及预后的关系。方法选取我院2013年1月-2014年12月住院的脑梗死患者54例,根据病情程度分为重型组17例、中型组18例、轻型组19例,对选取的患者在入院后第1、3、5、7天进行hs-CRP水平的测定,另选取54例健康人群作为对照,并将测定结果进行比较。结果对照组hs-CRP水平为(5.1±1.1)mg/L,脑梗死组为(11.1±3.4)mg/L,两组比较差异有统计学意义(P<0.05);脑梗死组前3日hs-CRP水平显著上升;其中重型组在各个时段均高于其余两组;治疗后hs-CRP正常组总有效率为87.49%,异常组为63.33%,两组比较差异有统计学意义(P<0.05)。结论 hs-CRP水平在评估脑梗死病情与疗效观察中均具有非常重要的指导作用。
Objective To investigate the relationship between the level of hs-CRP and the severity and prognosis of patients with cerebral infarction. Methods Fifty-four patients with cerebral infarction hospitalized from January 2013 to December 2014 in our hospital were divided into severe group (17 cases), medium group (18 cases) and light group (19 cases). According to the severity of illness, , 3,5,7 days hs-CRP levels were measured, the other 54 healthy people as a control, and the results were compared. Results The level of hs-CRP in the control group was (5.1 ± 1.1) mg / L and (11.1 ± 3.4) mg / L in the cerebral infarction group, the difference was statistically significant (P <0.05) hs-CRP levels were significantly increased; among them, the heavy-duty group was higher than the other two groups at various time points; the total effective rate of the normal hs-CRP group was 87.49% and the abnormal group was 63.33%, the difference was statistically significant <0.05). Conclusion The level of hs-CRP plays a very important guiding role in the assessment of the status of cerebral infarction and the observation of curative effect.