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加拿大卫生部于2007-11-11批准Merck Frosst Canada,Ltd生产的raltegravir片剂(Isentress)与其他抗逆转录病毒药物联用,治疗先前接受过治疗但仍存在病毒复制和多药耐药病毒株的HIV-1感染者。
Health Canada on November 11, 2007 approved raltegravir tablets (Isentress) from Merck Frosst Canada, Ltd in combination with other antiretroviral drugs to treat previously treated but still viral replication and multi-drug resistant strains Of HIV-1 infected persons.