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作者原推想真核激发因子 4 E蛋白升高预示 1～ 3期乳腺癌患者的高复发率。已知肿瘤大小和淋巴结状态是乳腺癌中两个最重要的独立性预后指标 ,但 4 E蛋白是调节 m RNA蛋白合成的重要因子 ,可列为乳腺癌复发的独立性预测指标。L ouisiana州大学外科等单位曾对 191例 1～ 3期乳腺
The authors hypothesize that elevated eukaryotic factor 4 E protein predicts high recurrence rates in patients with stage 1-3 breast cancer. Known tumor size and lymph node status are two of the most important independent prognostic markers in breast cancer, but 4E protein is an important factor in the regulation of m RNA protein synthesis and may be an independent predictor of breast cancer recurrence. L ouisiana State University surgery and other units had 191 cases of 1 to 3 of the breast