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尽管抗高血压药物研究有进展,仍然有部分高血压患者的血压经规范的降压治疗无法达标,成为临床上棘手的难治性高血压(顽固性高血压)[1]。此类患者在服用3种降压药(其中一种是利尿药)至最大剂量或最大耐受后血压仍然得不到有效的控制。去肾交感神经术(renal denervation,RDN)是一种新兴技术,通过阻断肾交感神经,降低交感神经兴奋性而达到降压目的。多项临床研究显示这种技术有可能显著且安全地
Despite advances in antihypertensive drug research, there are still some patients with hypertension who are unable to achieve standard blood pressure control and become clinically intractable hypertension (intractable hypertension) [1]. Such patients taking three kinds of antihypertensive drugs (one is a diuretic) to the maximum dose or maximum tolerated blood pressure is still not effectively controlled. Renal denervation (RDN) is an emerging technology that achieves the goal of lowering blood pressure by blocking the renal sympathetic nerve and decreasing the excitability of sympathetic nerves. Several clinical studies have shown that this technique is potentially significant and safe