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为了检验血浆肾素活性对高血压患者的预后价值,在一项系统定点治疗方案中,作者检测了1717例(平均年龄53岁,白人36%,男性67%)轻至中度高血压病人治疗前的肾素-钠水平。方法肾素水平是经绘制血浆肾素活性-尿排钠量坐标图而取得,并将其分为高(12％)、正常(56％)、低(32%)肾素三组,其中可以预料在年龄、性别和种族之间存在变异。但三组病人均未参考肾素水平,而给予相似的改进的阶梯治疗。结果进入试验时高肾素组血压为20.13±2.5/1.3±1.3kPa,正常肾素组血压为 20.13±2.5/12.93±1.3kPa,低肾素组血压为 20.13±2.7/12.8±1.47kPa。随访8.3年中27例发生心肌梗塞(MI)。将年龄、性别和种族校正后,每千人年的AMI发生
To test the prognostic value of plasma renin activity in patients with hypertension, in a systematic targeted therapy regimen, the authors tested 1717 patients (mean age 53 years, whites 36%, males 67%) with mild-to-moderate hypertension Pre-renin-sodium levels. Methods Renin levels were obtained by plotting plasma renin activity-urinary sodium output and divided into three groups: high (12%), normal (56%) and low (32%) renin Variation is expected between age, gender and race. However, no reference was made to renin levels in all three groups, but a similar and improved step treatment was given. Results The blood pressure was 20.13 ± 2.5 / 1.3 ± 1.3kPa in the high-renin group and 20.13 ± 2.5 / 12.93 ± 1.3kPa in the normal renin group and 20.13 ± 2.7 / 12.8 ± 1.47 kPa in the low renin group. Follow-up 8.3 years in 27 cases of myocardial infarction (MI). AMI occurs every thousand years after age, gender and ethnicity are corrected