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文献报道,消炎痛治疗炎症疗效很高,这个非固醇类抗炎剂,具有明显的抗渗出、解热、抗增生、抗过敏和止痛作用,还有免疫调节作用;而且能较好地吸附在粘膜上,促使进入炎症灶,所以可用于局部治疗。作者用消炎痛软膏综合治疗牙周炎,观察中度和重度广泛性牙周炎60例,年龄23~45岁。以前曾多次使用抗菌药(呋喃西林、丁香酚、杀菌素等)治疗效果不佳,伴有牙周脓肿形成27例。用消炎痛局部治疗40例(基本组),未用消炎痛20例(对照组)。两组都进行口腔卫生训练,同时消除局部刺激因素,每天用0.2%洗必太冲洗龈袋并湿敷10分钟。另外,基本组用有延迟作用的3%消炎痛软膏(用聚乙烯乙二醇作延迟剂),制成塞治剂放入牙周袋,龈缘放牙周保护剂。急性炎症
Reported in the literature, indomethacin treatment of inflammation is highly effective, this non-steroidal anti-inflammatory agents, with significant anti-exudative, antipyretic, anti-proliferative, anti-allergic and analgesic effects, as well as immune regulation; Adsorption on the mucosa, to promote inflammation into the stove, it can be used for local treatment. The author used indomethacin ointment comprehensive treatment of periodontitis, observed in 60 cases of moderate and severe generalized periodontitis, aged 23 to 45 years. Previously, repeated use of antibacterial drugs (nitrofurazone, eugenol, spinosad, etc.) poor treatment, with the formation of periodontal abscess in 27 cases. With indomethacin local treatment of 40 cases (basic group), indomethacin 20 cases (control group). Both groups performed oral hygiene training while eliminating local irritants, flushing the gingival pouch with 0.2% chlorhexidine daily for 10 minutes. In addition, the basic group with a delay of 3% indomethacin ointment (with polyethylene glycol as a delay agent), made into a plug agent in the periodontal pocket, gingival margin periodontal protection agent. Acute inflammation