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有相当数量的消化性溃疡表现为溃疡穿孔或溃疡出血,而既往无消化不良的病史。临床报道消化性溃病的发病率为5～10%不等,而尸检报道为3～24%不等,这是由于有些消化性溃疡病者终生无症状。溃疡穿孔和出血在所有穿孔病人中,先前无消化不良症状而突然发生穿孔者约占1/3。对先前无症状的溃疡穿孔病人仅作缝合术,而未施行切除术或迷走神经切断术等,随访数年,其症状复发率仅10～20%。而穿孔前就有消化不良症状者其复发率高达69～96%。抗炎药的应用与穿孔前的消化不良症状也有关联,据报道先前无症状者41%有服抗炎药,而有症状者仅17%有服抗炎药。据观察无症状性“非穿透性溃疡”与“穿透性溃疡”穿孔的预后都较好。
A significant number of peptic ulcer bleeding ulcer perforation or ulcer performance, but no past history of indigestion. Clinical reports of the incidence of peptic ulcer disease ranging from 5 to 10%, while the autopsy reported ranged from 3 to 24%, which is due to some life-long symptoms of peptic ulcer disease. Perforation and Bleeding of Ulcers In all patients with perforation, approximately one-third of all perforation occurred without previous symptoms of dyspepsia. For previously asymptomatic ulcer perforation patients only for suture, without the implementation of resection or vagotomy, etc., followed up for several years, the recurrence rate of 10% of their symptoms only. Perforation before there are symptoms of dyspepsia its recurrence rate as high as 69 to 96%. The use of anti-inflammatory drugs is also associated with pre-perforation dyspepsia, with 41% of previously asymptomatic anti-inflammatory drugs reported and only 17% of those with symptomatic anti-inflammatory drugs. It has been observed that asymptomatic “non-penetrating ulcer” and “penetrating ulcer” perforation have better prognosis.