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布洛芬系一种非类固醇抗炎药,其治疗高山性(high-altitude)头痛的疗效优于安慰剂。本文采用随机、双盲试验,比较了口服布洛芬与舒马曲坦(sumatriptan)(5-HT1受体激动剂)治疗高山性头痛的疗效。33例健康自愿者(平均年龄27岁)被送到海拔3480米高处,停留18小时。5~15
Ibuprofen, a non-steroidal anti-inflammatory drug, is superior to placebo in the treatment of high-altitude headaches. This randomized, double-blind trial compared the efficacy of oral ibuprofen with sumatriptan (a 5-HT1 receptor agonist) in the treatment of mountain headache. Thirty-three healthy volunteers (mean age 27 years) were sent to an altitude of 3480 meters for 18 hours. 5 ~ 15