目的建立一种简便、快速、敏感、特异的检测血吸虫抗体的新方法。方法用滴金免疫测定法（DIGFA）检测血吸虫病人血清抗体，并以ELISA作平行对照。结果DIGFA和ELISA的敏感性分别为97．1％和95．7％；特异性分别为99．1％和100％，两法无显著差异（P＞0．05）。62份其它寄生虫感染血清，除肺吸虫1例，ELISA呈阳性反应外，其余均为阴性。结论实验结果不仅显示了DIGFA的敏感性和特异性与ELISA相似，而且具有简便、快速、不需要特殊设备等优点，是一种值得推广应用的检测血吸虫抗体的新方法。 Objective To establish a simple, rapid, sensitive and specific method for the detection of schistosome antibodies. Methods Serum antibodies of schistosomiasis patients were detected by DIGFA and parallel with ELISA. Results The sensitivity of DIGFA and ELISA were 97.1% and 95.7%, respectively. The specificity was 99.1% and 100% respectively. There was no significant difference between the two methods (P> 0.05). Sixty-two other parasite-infected sera, except for Paragonimus, showed positive ELISA, but the others were negative. Conclusion The experimental results not only show that the sensitivity and specificity of DIGFA are similar to those of ELISA, but also have the advantages of being simple, rapid, and do not need special equipment. It is a new method to detect schistosome antibodies.