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目的了解四川省凉山彝族自治州地区吸毒人群直接和间接共用注射器具静脉吸毒方式与HIV感染的关系。方法于2004年5月至7月,从社区中招募吸毒人群调查其社会人口学特征、近3个月直接和间接共用注射器具静脉吸毒方式、近6个月性行为情况。采集研究对象的血样进行HIV抗体检测。结果在调查的吸毒人群中HIV感染率为15.1%(68/451),其中静脉吸毒人群HIV感染率为17.8%(66/370)。多因素Logistic分析结果显示,民族(OR为2.40;95%CI为1.39~4.13)、近3个月共用针头和注射器(OR为2.02;95%CI为1.12~3.63)、近3个月共用洗针头或注射器用水(OR,4.00;95%;CI,1.28~12.54)与HIV感染关系有统计学意义。结论四川省凉山彝族自治州吸毒人群HIV感染率高,直接和间接共用注射器具静脉吸毒行为以及高危性行为普遍,应加强对此类行为的干预。
Objective To understand the relationship between direct and indirect intravenous drug use and HIV infection among drug users in Liangshan Yi Autonomous Prefecture in Sichuan Province. METHODS: From May to July 2004, drug abusers were recruited from the community to investigate their socio-demographic characteristics. In the past 3 months, they directly and indirectly shared the use of intravenous drug-injecting devices and sexual behavior for nearly 6 months. Blood samples were collected for HIV antibody testing. Results HIV prevalence was 15.1% (68/451) among drug users surveyed, among which HIV infection rate was 17.8% (66/370) in intravenous drug users. Multivariate Logistic analysis showed that the nationalities (OR = 2.40; 95% CI: 1.39-4.13) shared needles and syringes in nearly 3 months (OR = 2.02; 95% CI: 1.12-3.63) The water used for needle or syringe (OR, 4.00; 95%; CI, 1.28-12.54) had a statistically significant relationship with HIV infection. Conclusion HIV infection rates among drug users in Liangshan Yi Autonomous Prefecture in Sichuan Province are high. Both direct and indirect intravenous drug use and high-risk behaviors of injecting devices are common. Intervention should be strengthened.