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本文旨在研究血清铁蛋白及铁的其它指示物是否影响老年心肌梗死(MI)的发生。对象与方法自1990～1996年,作者对7983名老年人(年龄≥55岁)进行随访,最终共选择172名进行了血清铁蛋白和MI危险性分析,其中初发MI患者60名,无心脏病对照组112名。收集基线时血样,以测量铁蛋白、铁、转铁蛋白、血浆铜蓝蛋白和C反应蛋白的浓度。用分组(nested)病例对照法观察血清铁蛋白和致命及非致命MI的关系。用计算机问卷收集健康状况、病史、用药史、教育、收入及吸烟行为资料。用半定量食物频率问卷收集饮食资料,以取得饮食总铁及血红素铁的数据。
This article aims to investigate whether serum ferritin and other iron indicators affect the incidence of senile myocardial infarction (MI). Subjects and Methods From 1990 to 1996, the authors followed 7,983 elderly (≥55 years of age) and eventually selected a total of 172 patients for risk analysis of serum ferritin and MI, of which 60 were initially MI, without heart disease The control group of 112. Blood samples were collected at baseline to measure the concentrations of ferritin, iron, transferrin, ceruloplasmin, and C-reactive protein. The relationship between serum ferritin and lethal and non-fatal MI was observed using a nested case-control study. A computerized questionnaire was used to collect information on health status, medical history, medication history, education, income and smoking behavior. Dietary information was collected using a semi-quantitative food frequency questionnaire to obtain data on dietary total iron and heme iron.