论文部分内容阅读
10 December 2018? 2018 Huazhong University of Science and TechnologyLarge-cell neuroendocrine carcinoma (LCNEC) is a kind of neuroendocrine tumor (NET), which is extremely rare in the cranium. NETs are classified as high grade, like small cell carcinoma (SCC) and LCNEC, or low grade, like carcinoid (typical carcinoid and atypical carcinoid). Out of all these, SCC is the most common. LCNEC is extremely difficult to diagnose. Histology and immunohistochemistry (ICH) are considered to be useful for pathological diagnosis. The prognosis of intracranial LCNEC is very poor, and standard treatment remains unclear due to its rarity.