给正常大鼠腹腔注射人参、西洋参、三七的总皂甙(缩写为SPG、SPQ及SPNG),可引起肾上腺中维生素C含量降低(分别为36,41,41％)。但SPQ及SPG连续6天腹腔注射,可明显对抗ACTH引起的大鼠肾上腺维生素C的降低,并能减轻ACTH引起的小鼠胸腺及脾脏的萎缩,SPQ的作用强于SPG,SPNG则无上述作用。推测这种抗应激作用的差异,可能与三者所含的人参皂甙Rb与Rg的比例不同有关。 Intraperitoneal injection of ginsenosides, American ginseng, Panax notoginseng saponins (abbreviated as SPG, SPQ, and SPNG) into the normal rats caused a decrease in adrenal vitamin C content (36, 41, 41%, respectively). However, SPQ and SPG injected intraperitoneally for 6 consecutive days could significantly reduce the ACTH-induced decrease in adrenal vitamin C and reduce the atrophy of thymus and spleen in mice induced by ACTH. The effect of SPQ was stronger than that of SPG. SPNG had no such effect. . It is speculated that the difference in anti-stress effects may be related to the different ratios of ginsenoside Rb and Rg contained in the three.