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General surgery has been the clinical foundation for all of the branches of the surgical specialties.The scientific principles developed in general surgery have spread through the specialties as well.This is the basis for surgical mastery.The rapid development of information sciences brings great opportunities for further developments in general surgery.General surgeons will be challenged to learn how to incorporate these advances into their practice.Integrating other disciplines such as digital imaging will be required for general surgeons in the 21st century.General surgeons should not only understand the essence of traditional general surgery,but also be proficient in the usage of advanced diagnostic and therapeutic tools which will lead to promoting further developments in general surgery.