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涎腺辐射损伤是头颈部肿瘤放疗最常见的并发症和后遗症,其发生率高。涎腺辐射损伤导致唾液分泌量锐减,出现口腔干燥症,给患者造成极大痛苦,严重地影响患者的生存质量,是放疗中急待解决的问题。目前尚无完全有效的预防和治疗方法,多采取对症治疗。本文就涎腺辐射损伤的发病机制及防治予以综述。
Salivary radiation damage is the most common head and neck cancer radiotherapy complications and sequelae, the high incidence. Salivary radiation damage caused saliva secretion dropped sharply, the emergence of xerostomia, causing great suffering to patients, seriously affecting the quality of life of patients is an urgent problem in radiotherapy. At present, there is no completely effective prevention and treatment methods, and more symptomatic treatment. This article reviews the pathogenesis and prevention of salivary radiation damage.