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目的:比较舒血宁注射液和参麦注射液联合宁心益脉汤治疗病毒性心肌炎的临床效果。方法:选择2013年11月—2016年6月之间到医院心内科就诊的64例病毒性心肌炎患者,按照随机数字的方法将64例患者分为两组,对照组和观察组,每组32例患者,对照组患者采取纯西医疗法,观察组患者在对照组的治疗方法基础上,使用中医药治疗方法,对比治疗的效果。结果:对照组和观察组患者在开始治疗前的肌酸磷酸激酶(以下简称CK)和肌酸磷酸激酶的同工酶(以下简称CK-MB)在开始治疗前的数据差异均不具有统计学意义(t=0.856,0.140,P>0.05),在经过治疗后,两个组别的CK和CK-MB均出现了降低,而且数据差异具有统计学意义(t=18.299,21.489,7.118,14.181,P<0.05),对治疗后的数据比较结果发现,两组的CK和CK-MB均为观察组的低于对照组的,而且数据差异具有统计学意义(t=7.209,7.314,P<0.05),对照组患者的临床治疗效果总有效率为68.75%,观察组患者的临床治疗效果总有效率为90.63%,两个组别的数据比较差异具有统计学意义(χ~2=4.730,P=0.030)。结论:舒血宁注射液和参麦注射液联合宁心益脉汤治疗病毒性心肌炎,能够对心肌细胞产生保护作用,改善患者的临床症状,将临床治愈率提高,值得在更大的临床范围内推广。
Objective: To compare the clinical effects of Shuxuening Injection and Shenmai Injection combined with Ningxin Yimai Decoction in the treatment of viral myocarditis. Methods: A total of 64 patients with viral myocarditis from November 2013 to June 2016 who visited the cardiology department of the hospital were divided into two groups according to the random number method: control group and observation group, with 32 Cases of patients, the control group of patients with pure Western medical treatment, observation group patients in the control group based on the treatment method, the use of traditional Chinese medicine treatment methods, compared the effect of treatment. Results: There was no statistical difference in the data of CK-MB and creatine phosphokinase (CK-MB) between the control group and the observation group before the start of treatment before the start of treatment (T = 0.856,0.140, P> 0.05). After treatment, the CK and CK-MB in both groups decreased, and the difference was statistically significant (t = 18.299,21.489,7.118,14.181 , P <0.05). The comparison of data after treatment showed that both CK and CK-MB in the two groups were lower than the control group, and the difference was statistically significant (t = 7.209, 7.314, P < 0.05). The total effective rate of clinical treatment in control group was 68.75%. The total effective rate of clinical treatment in observation group was 90.63%. There was significant difference between the two groups (χ ~ 2 = 4.730, P = 0.030). Conclusion: Shuxuening injection and Shenmai injection combined with Ningxin Yimai Tang in the treatment of viral myocarditis can exert protective effect on cardiomyocytes and improve the clinical symptoms of patients, and will improve the clinical cure rate, which deserves further clinical application Within the promotion.