自身免疫是指机体的免疫功能损伤了自身组织而引起的免疫反应。自身免疫与自身免疫病的形成,是由于人体免疫系统自我识别功能的破坏。其机理一是对自身抗原的正常耐受性的逃脱(Evasion),如隐蔽抗原的释放和抗原性改变;二是耐受机制的破坏,出现了不正常的抗体。自身免疫性疾病常有高γ球蛋白和多种自身抗体, Autoimmune refers to the body’s immune function damage to their own organization caused by the immune response. The formation of autoimmune and autoimmune diseases is due to the destruction of the self-recognition function of the human immune system. One mechanism is the escape of normal tolerance to self antigens (Evasion), such as the release of hidden antigens and antigenic changes; the second is the destruction of tolerance mechanisms, the emergence of abnormal antibodies. Autoimmune diseases often have high-gamma globulin and a variety of autoantibodies,