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顽固性色素膜炎的发病机理与机体的免疫功能失调有关。1976年以来,我们用免疫疗法先后治疗了18例顽固性色素膜炎,取得了满意的疗效。一般资料本组18例中,男11例,女7例。年龄最小6岁,最大48岁。其中交感性眼炎2例,Behcet氏病4例,小柳——原田氏病3例,周边部色素膜炎2例,全色素膜炎7例。其中采用环磷酰胺治疗的有15例,14例有效,1例无效,后者改用6—巯基嘌呤(6—MP),其余3例采用转移因子治疗。视力均有大幅度提高,眼部症状明显好转。
The pathogenesis of intractable uveitis is related to the immune dysfunction of the body. Since 1976, we have treated 18 cases of intractable uveitis with immunotherapy and achieved satisfactory results. General Information The group of 18 patients, 11 males and 7 females. Youngest 6 years old, maximum 48 years old. Among them, 2 cases of sympathetic ophthalmia, 4 cases of Behcet’s disease, 3 cases of Koyanagi-Harada disease, 2 cases of peripheral uveitis, and 7 cases of uveitis. Among them, 15 cases were treated with cyclophosphamide, 14 cases were effective, and 1 case was ineffective. The latter was replaced by 6-mercaptopurine (6-MP) and the remaining 3 cases were treated with transfer factor. Visual acuity has significantly increased, eye symptoms improved significantly.