对抗生素所致的出血倾向是值得临床重视的问题。现将我院1983年5月至1991年5月住院新生儿中,在应用抗生素后,观察562例发生抗生素相关性出血14例报告如下。临床资料一、病例选择用抗生素前均经过出凝血功能障碍的筛选检查,排除其他与抗生素无关的若干因素,全组562例用抗生素后发生出血14例,男性8例,女性6例。发病年龄7～28天。二、出血的临床类型与预后主要表现以针刺部位出血不止6例,皮 Bleeding propensity to antibiotics is a problem that deserves clinical attention. Now in our hospital from May 1983 to May 1991 hospitalized newborns, after the application of antibiotics, observed in 562 cases of antibiotic-associated bleeding in 14 cases reported as follows. Clinical data A selection of patients with antibiotics have been through coagulation disorders screening test to exclude other factors unrelated to antibiotics, the whole group of 562 patients after bleeding with antibiotics in 14 cases, 8 males and 6 females. Age of onset of 7 to 28 days. Second, the clinical manifestations and prognosis of bleeding mainly in the acupuncture site bleeding more than 6 cases, skin