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目的 分析超低出生体质量儿(ELBW)常见并发症的发生率及防治措施。方法 对16例ELBW和26例极低出生体质量儿(VLBW)的并发症[肺透明膜病(NRDS)、支气管肺发育不良(BPD)、动脉导管未闭(PDA)、脑室内出血(IVH)、脑室周围白质软化(PVL)、早产儿视网膜病(ROP)]进行分析。结果 ELBW并NRDS、BPD、PDA、IVH、PVL、ROP发生率分别为81%、81%、25%、50%、13%、63%;VLBW并NRDS、BPD、PDA、IVH、PVL、ROP的发生率分别为88%、42%、42%、50%、12%、54%。BPD发生率ELBW较VLBW显著增高(P<0.05)。NRDS、BPD、PDA均治愈,ROP无致盲病例。ELBW组2例PVL并Ⅲ、Ⅳ度IVH,随诊出现脑瘫。结论 ELBW并发症中NRDS、BPD、ROP、IVH发生率高,Ⅲ度以上IVH和PVL是影响ELBW远期预后重要因素。
Objective To analyze the incidence and prevention and treatment of common complications of ELBW. Methods Sixteen patients with ELBW and 26 VLBW complications [hyaline membrane disease (NRDS), bronchopulmonary dysplasia (BPD), patent ductus arteriosus (PDA), intraventricular hemorrhage (IVH) , Periventricular leukomalacia (PVL), retinopathy of prematurity (ROP)] were analyzed. Results The incidences of ELBW with NRDS, BPD, PDA, IVH, PVL and ROP were 81%, 81%, 25%, 50%, 13% and 63% The incidence rates were 88%, 42%, 42%, 50%, 12% and 54% respectively. The incidence of BPD was significantly higher than that of VLBW (P <0.05). NRDS, BPD, PDA were cured, ROP no blind cases. ELBW group 2 PVL and Ⅲ, Ⅳ degree IVH, follow-up appeared cerebral palsy. Conclusions The incidence of NRDS, BPD, ROP and IVH in ELBW complications is high. IVH and PVL above Ⅲ degrees are the important factors that influence the long-term prognosis of ELBW.