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目的:研究有上消化道症状的患者幽门螺杆菌(helicobacter pylori,Hp)感染状况及其与胃食管反流病(GERD)的相关性。方法:抽取南京军区福州总医院消化内科门诊病人中有上消化道症状者进行问卷调查并进行14C-尿素呼气试验检测Hp感染,用中文版反流性疾病问卷(reflux diagnostic questionnaires,RDQ)调查GERD患病情况,分析Hp感染与GERD患病的关系。结果:共调查219例,Hp感染率63.01%,男女比例1:1.607,各年龄组感染率比较差异无统计学意义(P>0.05),吸烟组与非吸烟组、饮酒组与非饮酒组Hp感染率差异亦无统计学意义(P>0.05),Hp阳性调查者GERD患病率低于Hp阴性调查者(P<0.05)。结论:Hp在有上消化道症状的人群中感染率高,Hp阳性者GERD患病率较低。
Objective: To investigate the infection of Helicobacter pylori (Hp) and its relationship with gastroesophageal reflux disease (GERD) in patients with upper gastrointestinal symptoms. Methods: The patients with upper gastrointestinal symptoms from outpatients of gastroenterology department of Fuzhou General Hospital of Nanjing Military Region were investigated by questionnaire and 14C-urea breath test was used to detect Hp infection. The Chinese version of reflux diagnostic questionnaires (RDQ) GERD prevalence, analyze the relationship between Hp infection and GERD prevalence. Results: A total of 219 cases were investigated, the infection rate of Hp was 63.01%, the ratio of male to female was 1: 1.607, there was no significant difference in the infection rate among all age groups (P> 0.05). The smoking and non-smoking groups, There was no significant difference in infection rate (P> 0.05). The prevalence of GERD in Hp-positive subjects was lower than that in Hp-negative subjects (P <0.05). Conclusions: The prevalence of Hp in people with upper gastrointestinal symptoms is high, and the prevalence of Hp-positive GERD is lower.