论文部分内容阅读
目的探讨液基细胞薄层涂片检查(thin-prep cytology test,TCT)在膀胱肿瘤诊断中的价值及临床意义。方法收集78例确诊膀胱上皮癌患者的尿液,同时进行尿液传统涂片细胞学检查和TCT细胞病理学检查。结果尿液传统涂片细胞学检查和TCT对膀胱上皮癌诊断的敏感性分别为74.36和88.46(P<0.05)。其中34例病理为非浸润性膀胱上皮癌低级别,2种方法诊断的敏感性分别为67.65和88.24(P<0.05);23例病理为非浸润性膀胱上皮癌高级别,2种方法敏感性分别为78.26和86.96(P>0.05);21例病理为浸润性膀胱上皮癌,2种方法敏感性分别为80.95和90.48(P>0.05)。78例中25例为复发性膀胱癌患者,2种方法诊断的敏感性分别为68.00和84.00(P<0.05)。结论尿液标本TCT优于传统涂片法,可显著提高膀胱癌的诊断率。
Objective To investigate the value and clinical significance of thin-prep cytology test (TCT) in the diagnosis of bladder cancer. Methods Urine was collected from 78 patients diagnosed with epithelial ovarian cancer. Meanwhile, urine smear cytology and TCT cytopathology were performed simultaneously. Results The sensitivity of urine smear cytology and TCT to the diagnosis of bladder epithelial carcinoma were 74.36 and 88.46, respectively (P <0.05). Among them 34 cases were non-invasive bladder epithelial carcinoma with low grade, the diagnostic sensitivity of the two methods were 67.65 and 88.24 respectively (P <0.05); 23 cases were non-invasive bladder epithelial carcinoma with high grade and the sensitivity of the two methods (78.26 and 86.96, respectively) (P> 0.05). The pathological results of 21 patients with invasive bladder epithelial carcinoma were 80.95 and 90.48, respectively (P> 0.05). Among the 78 cases, 25 cases were recurrent bladder cancer. The diagnostic sensitivity of the two methods were 68.00 and 84.00, respectively (P <0.05). Conclusion Urine samples TCT better than the traditional smear method can significantly improve the diagnostic rate of bladder cancer.