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对UCLA医疗中心1955～1987年间29例头颈部纤维肉瘤病例作了回顾性复习。年龄2一69岁,平均35岁,18岁以下9例。男女比例15∶14。2例纤维肉瘤发生部位有放射历史(1例13年前,1例6年前)。29例中低度恶性15例,高度恶性13例。手术方法:4例肿瘤小于5cm局部切除(切除肿瘤+足够切缘);18例整块切除(切除肿瘤累及的整个解剖区域+广泛的切缘)。放射治疗剂量4 480～6 900 cGy,平均5 500cGy。化疗制剂用氮烯咪胺,阿霉素,环磷酰胺,长春新碱及顺铂等。
A review of 29 cases of head and neck fibrosarcoma at UCLA Medical Center from 1955 to 1987 was retrospectively reviewed. Age 2 to 69 years, average 35 years old, 9 cases under 18 years old. The ratio of males to females was 15:14. There were radiological histories in the sites of the 2 cases of fibrosarcoma (1 case 13 years ago, 1 case 6 years ago). Twenty-nine cases had low-grade malignancy in 15 cases and high-grade malignancy in 13 cases. Surgical methods: 4 cases of tumors less than 5cm local resection (resection of tumor plus adequate margins); 18 cases of whole resection (excision of the entire anatomical region involved in the tumor + a wide margin). Radiation doses ranged from 4 480 to 6 900 cGy with an average of 5 500 cGy. Chemotherapeutic preparations include naltrexamine, doxorubicin, cyclophosphamide, vincristine and cisplatin.