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本项实验研究采用吡喹酮栓剂治疗家兔及小鼠实验性日本血吸虫病,结果证明在相同剂量条件下,吡喹酮栓剂组的平均减虫率优于吡喹酮口服组。肝脏虫卵肉芽肿检查亦以吡喹酮栓剂组较小,病变较轻。研究证明,吡喹酮肛栓投药是治疗血吸虫病的又一有效途径。
In this experiment, praziquantel suppository was used to treat experimental schistosomiasis japonica in rabbits and mice. The results showed that the average reduction rate of praziquantel suppository was better than that of praziquantel in the same dosage. Liver granuloma test also praziquantel suppository group smaller lesions less. Studies have shown that praziquantel anal suppository administration is another effective way to treat schistosomiasis.