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目前对羊水量的调节知之甚少,胎儿无尿引起羊水过少,胎儿吞咽异常导致羊水过多。作者希望通过羊水量的变化评价消炎痛治疗有症状羊水过多的可能性。作者收集8例羊水过多者,平均年龄26.6±4.4岁,孕龄28.6±3.5周。主诉为早产和/或呼吸困难。排除胎儿结构异常和糖尿病患者。用胎儿膀胱容量变化估计排尿量。B超下穿刺羊膜腔放水缓解症状并检查染色体;将对氨马尿酸400mg注入羊膜腔中,20分钟后再抽3 ml羊水并取出穿刺针。症状复发时再次穿刺羊膜减压,测残余对氨马尿酸量,再注药并重复上次操作。然后口服消炎痛25mg每6小时1次。用药后24小时内做胎儿超声心动
Currently little knowledge of the regulation of amniotic fluid, fetal oliguria caused by oligohydramnios, fetal abnormalities leading to excessive amniotic fluid. The authors hope to evaluate the possibility of indomethacin in the treatment of symptomatic polyhydramnios by changing the amount of amniotic fluid. The authors collected 8 cases of polyhydramnios, with an average age of 26.6 ± 4.4 years, gestational age 28.6 ± 3.5 weeks. The chief complaint was premature labor and / or dyspnea. Exclude fetal structural abnormalities and diabetic patients. Estimation of urinary volume with changes in fetal bladder volume. B ultrasound puncture amniotic drainage to relieve symptoms and check the chromosomes; will aminuric acid uric acid 400mg into the amniotic cavity, 20 minutes and then pumping 3ml amniotic fluid and remove the puncture needle. Recurrence of symptoms once again piercing amniotic membrane decompression, measuring the residual amount of ammonia and uric acid, and then inject the drug and repeat the previous operation. Then oral indomethacin 25mg once every 6 hours. Fetal echocardiography within 24 hours after treatment