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目的比较16层螺旋CT冠状动脉成像(16SCTCA)对男性和女性冠状动脉粥样硬化性心脏病(CAHD)的诊断价值。方法入选疑诊为CAHD的受检者共105例(男61例,女44例),对其分别行16SCTCA检查和选择性冠状动脉造影(CAG)检查,以CAG为诊断CAHD的金标准,评估检查结果。结果105例受检者中,16SCTCA共显示1 184个冠状动脉节段可进行评价。16SCTCA诊断男性受检者冠状动脉显著狭窄的敏感性为93.6%,特异性为95.1%,阳性预测值为73.9%,阴性预测值为99.0%,符合率为94.9%;诊断女性受检者冠状动脉显著狭窄的敏感性为84.1%,特异性为94.4%,阳性预测值为77.9%,阴性预测值为96.2%,符合率为92.4%;女性受检者接受16SCTCA检查诊断冠状动脉显著狭窄的敏感性和阴性预测值低于男性(P<0.05)。结论16SCTCA在显示冠状动脉病变时具有较高的诊断准确率,尤其适用于男性。
Objective To compare the diagnostic value of 16-slice spiral CT coronary angiography (16SCTCA) for coronary heart disease (CAHD) in both men and women. Methods A total of 105 subjects (61 males and 44 females) suspected of having CAHD were enrolled in the study. 16SCTCA and selective coronary angiography (CAG) were performed respectively. The gold standard for the diagnosis of CAHD was evaluated by CAG. test result. Results Among the 105 subjects, 1684TCS showed a total of 1 184 coronary artery segments for evaluation. The sensitivity of 16SCTCA in diagnosing significant stenosis of coronary arteries in male subjects was 93.6%, specificity was 95.1%, positive predictive value was 73.9%, negative predictive value was 99.0% and coincidence rate was 94.9% Significantly narrowed sensitivity was 84.1%, specificity was 94.4%, positive predictive value was 77.9%, negative predictive value was 96.2%, coincidence rate was 92.4%; female subjects underwent 16SCTCA diagnosis of significant coronary stenosis sensitivity And negative predictive value was lower than male (P <0.05). Conclusion 16SCTCA has high diagnostic accuracy in displaying coronary artery lesions, especially for males.