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目的探究早发冠心病急性心肌梗死患者采用不同他汀类药物治疗的近期效果与心电图表现。方法取本院2013年6月~2015年8月收治的76例早发冠心病急性心肌梗死患者,并采用抽签的方式将其分为两组,对照组采用阿托伐他汀治疗,观察组采用瑞舒伐他汀治疗。并对两组患者的临床效果与心电图表现进行观察。结果观察组与对照组患者总胆固醇、空腹血糖、C反应蛋白以及低密度脂蛋白水平的对比(P>0.05);两组患者治疗后,1d内有关导联的STE比治疗前明显降低超过一半;治疗1d内ST段抬高导联产生T波倒置的现象,胸痛症状明显改善,心功能得到有效保护。结论早发冠心病急性心肌梗死患者采用不同他汀类药物治疗的近期效果相近,心电图表现类似。
Objective To investigate the short-term effect and electrocardiogram (ECG) of patients with premature coronary heart disease with acute myocardial infarction treated with different statins. Methods Totally 76 patients with acute myocardial infarction with premature coronary heart disease were enrolled in our hospital from June 2013 to August 2015. They were divided into two groups by random selection and the patients in the control group were treated with atorvastatin. Rosuvastatin treatment. The clinical effects and ECG findings of the two groups were also observed. Results The total cholesterol, fasting blood glucose, C-reactive protein and low density lipoprotein in observation group and control group were significantly lower than those before treatment (P> 0.05) ; ST-segment elevation leads to T-wave inversion within 1 day of treatment, with obvious improvement of chest pain symptoms and effective protection of cardiac function. Conclusions The recent effects of different statins in patients with premature coronary heart disease with acute myocardial infarction are similar, with similar ECG findings.