伴发EEG广泛性棘波的持续性精神、行为改变,一般归于小发作状态内。初发于中年以上患者的小发作状态,作者曾报告6例指出典型儿童失神发作特征不同。本文报导因急性持续性精神错乱或行为改变者11例。除1例有可疑癫痫病史外余均无癫痫史。平均年龄61±9.8岁(范围为42～76岁)。5男,6女。其中5例初诊为急性精神病、精神分裂症、碳酸锂中毒。本组患者经EEG确定后,均详细收集病史并作长达5年的临床和EEG随访。患者临床表现多数呈急性发作,持续1天～2月,均有精神改变,自轻度定向力障碍到精神错乱不等。但无一例有木僵或昏迷。4例有幻觉和妄想。此外如恐惧感、蜡样屈曲、错觉、情绪波动及逃跑意念等不常见。 7例说话缓慢,8例有短暂的额叶征,2例Babinski氏征(+)。此外有2例尿失禁。9例有清 The persistent spike of EEG with spikes and behavioral changes associated with EEG generally falls into the minor episode. Initial episode of middle-aged patients in the small seizures, the authors have reported 6 cases that typical children with different characteristics of seizures. This article reports 11 cases of acute persistent confusion or behavioral changes. In addition to one case of suspected history of epilepsy, I have no history of epilepsy. The mean age was 61 ± 9.8 years (range, 42-76 years). 5 men and 6 women. Five cases were newly diagnosed as acute psychosis, schizophrenia and lithium carbonate poisoning. The group of patients identified by EEG, were collected in detail the history and for up to 5 years of clinical and EEG follow-up. The majority of patients with acute clinical manifestations of attack, sustained 1 day to 2 months, have mental changes, ranging from mild to disordered mental disorders. But no one was stupor or coma. 4 cases have hallucinations and delusions. In addition, such as fear, wax-like flexion, delusion, mood swings and escape ideas are not common. Seven patients were slow to speak, eight had transient frontal lobe signs, and two had Babinski’s sign (+). In addition, 2 cases of urinary incontinence. 9 cases have clear