目的设计制作一种新型细胞加载系统,能在相同条件下对细胞施加压缩应力或者牵张应力。方法利用弹性膜片应力应变呈线性关系的原理,进行细胞加力装置和微电脑运动控制器的设计。结果设计的细胞加载系统可精确控制施加应力大小和频率,初步的细胞加载试验表明设计达到预期效果。结论利用此新型周期性细胞压缩牵张仪建立的细胞加载模型,可模拟口腔正畸临床中,牙槽骨一侧细胞受压,一侧细胞受牵张的现象。 Objective To design a novel cell loading system that can apply compressive stress or stretch stress to cells under the same conditions. Methods Based on the principle of linear relationship between stress and strain of elastic diaphragm, the design of cell force device and microcomputer motion controller was carried out. Results The cell loading system was designed to precisely control the magnitude and frequency of stress applied. Preliminary cell loading tests showed that the design achieved the desired results. Conclusion The cellular loading model established by this new type of periodic cell compression distraction apparatus can simulate the phenomenon that the cells on one side of the alveolar bone are compressed and the cells on the side are distracted in the orthodontic clinic.