系统性红斑狼疮(以下简称 SLE)是一病因不明的自身免疫性全身结缔组织疾,近年来发病率有明显的增加。本病临床表现错综复杂,可累及多个系统,诊断应符合下列三项标准之一:(1)有皮肤病变,又合并内脏损害,而且红斑狼疮(LE)细胞检查阳性或皮肤活检阳性者;(2)虽无皮肤病变,但有多脏器损害,且 LE 细胞检查阳性者;(3)有多脏器损害,基本符合美国风湿病协会诊断标准,在14项临床表现中有4项以上阳性 Systemic lupus erythematosus (hereinafter referred to as SLE) is an unknown cause of autoimmune systemic connective tissue disease in recent years, a significant increase in the incidence. The clinical manifestations of this disease are complex and can involve multiple systems. The diagnosis should meet one of the following three criteria: (1) skin lesions with combined visceral lesions and positive LE or positive skin biopsies; 2) although there is no skin lesions, but there are multiple organ damage, and LE cells check positive; (3) multiple organ damage, basically in line with the American College of Rheumatology diagnostic criteria in 14 clinical manifestations of 4 or more positive