论文部分内容阅读
多年来研究者们收集了有关证据,证明疱疹病毒不仅存在于唇疱疹、流感症状、生殖器溃疡,而且也存在于冠状动脉疾病。此外,寻找癌症成因的科学家们也认为肿瘤抑制基因P_(53)的缺陷与细胞的失控生长有联系。细胞的失控生长可导致肿瘤。现在,这些看来互不相关的研究形成交叉之路。马里兰州贝塞斯达国家心、肺和血液研究所的细胞生物学家Edith·H·Speir解释说,巨细胞病毒是疱疹家族中的一员,产生一种看来可使蛋白质P_(53)失去作用的一种蛋白。其结果,血管内的平滑肌细胞能够不断增生,直到阻止血液流通为止。她和同事们研究为什么进行过血管成形术的人中有25％～50％的病人六个月内血管重
Over the years, researchers have collected evidence that the herpes virus exists not only in cold sores, flu symptoms, genital ulcers, but also in coronary artery disease. In addition, scientists looking for the cause of cancer also believe that defects in the tumor suppressor P_ (53) are linked to uncontrolled cell growth. Uncontrolled cell growth can lead to tumors. Now, these seemingly unrelated studies form the crossroads. Edith H. Speir, a cell biologist at the National Heart, Lung and Blood Institute in Bethesda, Maryland, explained that cytomegalovirus is a member of the herpes family that produces a protein that appears to make P_ (53) A protein that loses its effect As a result, intravascular smooth muscle cells continue to proliferate until blood circulation is stopped. She and her colleagues studied why 25% to 50% of patients who underwent angioplasty had a blood vessel within six months