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目的评价冠心病不稳定型心绞痛(UA)患者应用阿托代他汀的疗效和安全性。方法将108例不稳定型心绞痛患者随机分为A组(常规治疗加阿托伐他汀10mg/d)和B组(常规治疗加阿托伐他汀40mg/d),疗程6周,并观察疗效及不良反应。结果A组与B组疗效比较有显著性差异(P<0.05),未见明显不良反应。结论40mg剂量阿托伐他汀降脂在治疗不稳定型心绞痛患者中是安全有效的。
Objective To evaluate the efficacy and safety of atorvastatin in patients with unstable angina pectoris (UA). Methods A total of 108 patients with unstable angina pectoris were randomly divided into group A (conventional treatment plus atorvastatin 10 mg / d) and group B (conventional treatment plus atorvastatin 40 mg / d) for 6 weeks. The curative effect and Adverse reactions. Results There was significant difference between group A and group B (P <0.05), and no obvious adverse reaction was found. Conclusions A 40 mg dose of atorvastatin is safe and effective in the treatment of patients with unstable angina.