抑裂素译自Chalone一词。Chalone过去曾被译作“抑素”,因为这个词在1913年被开始采用时是指与Hormone(激素)作用相反的物质。但此后这个词很少见于生物学和医学文献中。60年代,Bullough & Laurence提出了内在抑制因素对细胞有丝分裂的负反馈作用学说时,选用了Chalone词作为此类分裂抑制物质的总称,具有了现在的含意。 概念 Bullough & Laurence根据他们用表皮细胞所获得的数据提出:抑裂素在细胞有丝分裂中起负反馈调节作用,从而维持正常成 Schizophrenia is translated from Chalone. Chalone used to be translated as “somatostatin” in the past, because the word was introduced in 1913 when it was used against the opposite of Hormone. But since then the word rare in biological and medical literature. In the 1960s, when Bullough & Laurence proposed the theory of negative feedback on the mitosis of intrinsic inhibitory factors, Chalone was chosen as the general term for such mitotic substances with the present meaning. The concept Bullough & Laurence suggests based on the data they obtained from epidermal cells that mitogen plays a negative feedback regulator of cell mitosis and thus remains normal