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狒狒有许多特点,特别是在免疫和免疫病理方面,可供作人体曼氏血吸虫病的动物模型。1,狒狒的免疫系统在性质方面与人类相似;2,在东非狒狒可作为曼氏血吸虫的保虫宿主,从而推测在狒狒和血吸虫之间建立了适应关系;3,即使是困难的,但狒狒似可产生对曼氏血吸虫的免疫力。此外,在病理方面,狒狒除了不出现干线型肝硬化外,与人也十分相似。根据以上所述,作者选用狒狒作了血吸虫病免疫学的研究。在4次试验中共
Baboons have many characteristics, particularly in animal models of human Schistosoma mansoni, in terms of immunity and immunopathology. 1, the baboon’s immune system is similar in character to humans; 2) the baboon can be used as a host for the conservation of Schistosoma mansoni in eastern Africa, presumably establishing an adaptation between baboon and schistosomes; 3, even if it is difficult, baboons May seem to produce immunity against Schistosoma mansoni. In addition, in terms of pathology, baboons are very similar to humans except for the absence of trunk cirrhosis. Based on the above, the author chose baboons for immunological studies of schistosomiasis. In 4 trials